TABLE 6

Categorisation of airway response to methacholine

PD20 μmol (μg)PC20 mg·mL−1Interpretation
>2 (>400)>16Normal
0.5–2.0 (100–400)4–16Borderline AHR
0.13–0.5 (25–100)1–4Mild AHR
0.03–0.13 (6–25)0.25–1Moderate AHR
<0.03 (<6)<0.25Marked AHR

PD20: provocative dose causing a 20% fall in forced expiratory volume in 1 s (FEV1); PC20: provocative concentration causing a 20% fall in FEV1; AHR: airway hyperresponsiveness. Information from [3].