TABLE 1

Subject characteristics from previously published studies from which prediction equations were made [57, 106, 107]

MalesFemalesCombined
Subjects248242490
Age years44±17 (18–93)45±18 (18–87)44±17 (18–93)
Weight kg76.7±9.4 (55.0–105.0)61.6±8.8 (44.0–95.0)69.3±11.8 (44.0–105.0)
Height cm176±8 (154–196)164±7 (147–182)170±10 (147–196)
Body mass index kg·m-224.7±2.5 (18.9–29.9)23.0±3.0 (17.2–29.8)23.8±2.9 (17.2–29.9)
DLNO mL·min−1·mmHg−1164±31 (67–235)119±25 (47–186)142±36 (47–235)
DLCO mL·min−1·mmHg−134.1±6.3 (11.9–49.9)25.1±5.3 (11.3–38.6)29.6±7.4 (11.3–49.9)
DMCO mL·min−1·mmHg−1161±39 (72–250)104±26 (33–182)133±44 (33–250)
VC mL78±16 (25–121)65±15 (30–105)72±17 (25–121)
DMCO/VC ratio min−1·mmHg−12.11±0.57 (1.01–4.03)1.63±0.40 (0.88–2.96)1.90±0.57 (0.88–4.03)
KCO mL·min−1·mmHg−1·L−14.9±0.8 (2.7–7.1)4.8±0.7 (3.0–6.8)4.9±0.8 (2.7–7.1)
KNO mL·min−1·mmHg−1·L−123.8±3.9 (13.7–34.2)22.8±3.2 (13.5–31.5)23.3±3.6 (13.5–34.2)
DLNO/DLCO ratio4.83±0.40 (3.83–5.82)4.74±0.39 (3.85–5.78)4.79±0.40 (3.83–5.82)
  • Data are presented as n or mean±sd (range). The alveolar–capillary membrane diffusing capacity for carbon monoxide (DMCO) and total volume of blood in the lung capillaries exposed to alveolar air (VC) values reported in these studies [57, 106, 107] have been recalculated according to the parameters listed in table 4. DLNO: diffusing capacity of the lung for nitric oxide; DLCO: diffusing capacity of the lung for carbon monoxide; KCO: rate of uptake of carbon monoxide from alveolar gas; KNO: rate of uptake of nitric oxide from alveolar gas.