TABLE 1

Overnight urinary F2-isoprostanes, noncorrected and corrected

	CPAP		CPAP-withdrawal		Treatment effect (95% CI)	p-value
	Baseline	2 weeks	Baseline	2 weeks	Treatment effect (95% CI)	p-value
Subjects n	11		12
Non-corrected F2-isoprostanes ng·mL⁻¹	3.1±1.3	3.4±1.4	3.2±1.4	2.2±0.8	−1.3 (−2.4–−0.1)	0.03
Creatinine mmol·L⁻¹	13.8±10.5	13.8±10.6	11.3±4.3	8.4±2.9	−3.0 (−8.0–1.9)	0.21
Urine volume mL	814±497	889±569	699±312	988±335	205 (−88–499)	0.16
Urinary excretion rate mL·h⁻¹	78.1±43.1	83.9±53.2	57.0±31.1	86.7±28.5	18.9 (−12.3–50.1)	0.22
Corrected F2-isoprostanes/creatinine ratio ng·μmol⁻¹	0.31±0.18	0.37±0.19	0.29±0.11	0.27±0.07	−0.1 (−0.23–0.03)	0.11
F2-isoprostanes production corrected by urine excretion rate ng·h⁻¹	216.6±120.7	251.7±145.8	168.2±116.3	182.8±78.7	−56.9 (−161.0–47.2)	0.26

Data are presented as mean±sd, unless otherwise stated. CPAP: continuous positive airway pressure.