TABLE 2

Association of air pollutants exposure with levels of FEV₁ % predicted and FVC % predicted

Outcome by window of exposure and model	PM_2.5 (for 2 µg·m⁻³)		PM₁₀ (for 5 µg·m⁻³)		NO₂ (for 10 µg·m⁻³)		O₃ (for 10 µg·m⁻³)
	Beta±se	p-value	Beta±se	p-value	Beta±se	p-value	Beta±se	p-value
FEV₁
12-month
M0	0.85±0.38	0.02	−0.13±0.76	0.86	−1.73±1.09	0.11	1.86±1.01	0.06
M1	0.82±0.38	0.03	0.64±0.78	0.41	−0.86±1.2	0.47	3.5±1.16	0.003
M2	0.82±0.38	0.03	0.58±0.78	0.46	−1.36±1.18	0.25	3.95±1.14	0.001
6-month
M0	0.14±0.24	0.56	−0.11±0.51	0.82	−2.36±0.88	0.01	0.91±0.42	0.03
M1	0.13±0.25	0.60	0.09±0.52	0.86	−1.62±0.95	0.09	0.72±0.43	0.10
M2	0.15±0.25	0.54	0.08±0.52	0.87	−1.84±0.95	0.05	0.78±0.43	0.07
FVC
12-month
M0	−0.78±0.32	0.01	−3.01±0.63	<0.0001	−3.26±0.93	0.0005	1.01±0.86	0.24
M1	−0.78±0.32	0.02	−2.55±0.66	0.0001	−2.28±1.05	0.03	1.89±1.01	0.06
M2	−0.75±0.32	0.02	−2.56±0.66	0.0001	−2.58±1.05	0.01	2.15±1.01	0.03
6-month
M0	−0.63±0.2	0.002	−1.67±0.43	<0.0001	−3.45±0.75	<0.0001	1.1±0.35	0.002
M1	−0.63±0.21	0.002	−1.52±0.44	0.0005	−2.63±0.82	0.001	0.85±0.36	0.02
M2	−0.61±0.21	0.003	−1.52±0.44	0.0005	−2.75±0.82	0.001	0.88±0.36	0.02

PM_x: particulate matter with an aerodynamic cross section of x µm; FEV₁: forced expiratory volume in 1 s; FVC: forced vital capacity; M0: crude model estimated on 520 patients (1833 measurements); M1: model adjusted on recipient age (continuous), sex, smoking status of both donor and recipient, body mass index (continuous), donor age, type of lung transplant, underlying disease, sex mismatch, anti-human leukocyte antigen antibodies, transplant centre, living area and, for the 6-month, 3-month and 1-month exposure, on temperature and humidity, estimated on 495 patients (1770 measurements); M2: M1 model further adjusted on treated Pseudomonas infection, cytomegalovirus treated disease, immunosuppression induction and acute rejection treated episodes, estimated on 487 patients (1751 measurements).