TABLE 5

Reference values for DLCO from studies that complied with the 2005 American Thoracic Society/European Respiratory Society DLCO standards

Author#YearCountryAgeSubjects
Thompson [129]2008Australia45–71 years498 male/474 female
Koopman [130]2011Netherlands7–18 years278 male/265 female
Garcia-Rio [131]2012Spain65–85 years169 male/262 female
Kim [132]2012USA and Australia5–19 years225 male/254 female
Thomas [133]2014Denmark5–17 yearsmale/female (297 total)
Michailopoulos [134]2015Greece18–91 years234 male/233 female
Verbanck [135]2016Belgium20–80 years128 male/124 female
  • DLCO: diffusing capacity of the lung for carbon monoxide. #: only studies with at least 100 males and 100 females are included. All of these reference values were derived using caucasian subjects. : test gas contained 19% oxygen (all other studies used test gas with 21% oxygen).