Results of the outcome measures
| T0 | Change# at T3 | Change# at T6 | Change# at T12 | Subjects with ≥20% improvement at T3/T6/T12 | Subjects with ≥20% worsening at T3/T6/T12 | p-value¶ | |
| Average steps per weekday | 0.811 | ||||||
| Intervention | 5717±418 | −512 (−1003–−21) | −593 (−1058–−128) | −1225 (−1712–−738) | 18/16/8 (25/24/13) | 24/22/28 (34/33/45) | |
| Usual care | 6011±402 | −635 (−1074–−156) | −833 (−1315–−352) | −1148 (−1651–−644) | 9/12/12 (13/19/20) | 22/23/27 (32/35/45) | |
| Average METs | 0.364 | ||||||
| Intervention | 1.5±0.05 | −0.061 (−0.15–0.03) | −0.057 (−0.15–0.04) | −0.055 (−0.15–0.04) | 8/9/4 (11/13/7) | 8/10/5 (11/15/8) | |
| Usual care | 1.57±0.05 | −0.061 (−0.15–0.03) | 0.021 (−0.09–0.13) | −0.105 (−0.22–0.01) | 5/6/5 (7/9/8) | 6/3/5 (9/5/8) | |
| 6MWD m | 0.585 | ||||||
| Intervention | 456±14 | 4.1 (−2.8–11.1) | 4.8 (−3.9–13.5) | 0.8 (−8.8–10.3) | 2/2/3 (2.8/3/4.8) | 0/0/1 (0/0/1.6) | |
| Usual care | 461±8 | 1.9 (−4.1–7.9) | 3.3 (−2.9–9.6) | 4 (−2.4–10.3) | 0/0/1 (0/0/1.7) | ||
| Dyspnoea (score 1–7) | 0.179 | ||||||
| Intervention | 4.84±0.15 | 0.17 (−0.45–0.38) | 0.11 (−0.14–0.35) | −0.17 (−0.44–0.09) | 11/14/12 (16/21/19) | 5/10/17 (7/15/27) | |
| Usual care | 4.79±0.15 | 0.01 (−0.21–0.23) | −0.13 (−0.33–0.08) | −0.08 (−0.3–0.14) | 16/7/9 (24/11/15) | 9/7/6 (13/11/10) | |
| Fatigue (score 1–7) | 0.018 | ||||||
| Intervention | 4.35±0.1 | 0.05 (−0.15–0.26) | −0.19 (−0.39–0.01) | −0.14 (−0.35–0.07) | 14/10/7 (20/15/11) | 7/13/14 (10/19/22) | |
| Usual care | 4.2±0.13 | −0.06 (−0.28–0.17) | 0.13 (−0.12–0.37) | −0.12 (−0.37–0.13) | 10/12/13 (15/19/22) | 8/11/12 (12/17/20) | |
| Emotional function (score 1–7) | 0.590 | ||||||
| Intervention | 4.93±0.09 | 0.01 (−0.14–0.16) | −0.03 (−0.18–0.12) | 0.09 (−0.07–0.24) | 9/8/7 (13/12/11) | 4/10/8 (6/15/13) | |
| Usual care | 4.76±0.13 | 0.11 (−0.04–0.27) | 0.04 (−0.11–0.19) | 0.19 (0.04–0.34) | 10/12/10 (15/19/17) | 5/8/5 (7/12/8) | |
| Mastery (score 1–7) | 0.154 | ||||||
| Intervention | 5.42±0.09 | −0.03 (−0.22–0.16) | −0.14 (−0.32–0.06) | −0.1 (−0.31–0.11) | 7/9/7 (10/13/11) | 5/13/9 (7/19/15) | |
| Usual care | 5.35±0.09 | −0.06 (−0.21–0.08) | 0.03 (−0.13–0.19) | −0.23 (−0.39–−0.06) | 6/8/6 (9/12/10) | 5/3/8 (7/5/1) | |
| BMI kg·m–2 | 0.458 | ||||||
| Intervention | 27.7±0.58 | 0.08 (−0.11–0.26) | 0.12 (−0.14–0.37) | −0.05 (−0.37–0.27) | |||
| Usual care | 26.7±0.6 | 0.06 (−0.13–0.26) | 0.32 (0.07–0.57) | 0.09 (−0.2–0.39) |
Data are presented as n, mean±se, change with baseline values or n (%), unless otherwise stated. T0: 0 months; T3: 3 months; T6: 6 months; T12: 12 months; MET: metabolic equivalent of task; 6MWD: 6-min walking distance; BMI: body mass index. #: change refers to difference compared with T0; ¶: group by time interaction refers to effect of the intervention.