Risk of mesothelioma in offspring by diagnosis period when first-degree relatives were diagnosed with cancer
| Parent | Sibling | Parent or sibling | ||||
| Cases | SIR (95% CI) | Cases | SIR (95% CI) | Cases | SIR (95% CI) | |
| Up to 2000 | ||||||
| Mesothelioma | 2 | 5.72 (0.54–21.02) | 3 | 9.82 (1.85–29.06)# | 5 | 7.62 (2.41–17.93)# |
| Kidney | 7 | 1.18 (0.47–2.45) | 1 | 0.42 (0.00–2.43) | 8 | 0.96 (0.41–1.90) |
| Urinary bladder | 8 | 0.91 (0.39–1.79) | 11 | 2.73 (1.35–4.90) | 19 | 1.46 (0.88–2.28) |
| 2001 and 2012 | ||||||
| Mesothelioma | 2 | 2.93 (0.28–10.79) | 7 | 13.90 (5.51–28.80)# | 9 | 7.59 (3.44–14.47)# |
| Kidney | 16 | 1.46 (0.83–2.38) | 13 | 3.10 (1.64–5.31)# | 29 | 1.90 (1.27–2.74)# |
| Urinary bladder | 21 | 1.27 (0.79–1.95) | 12 | 1.72 (0.88–3.01) | 34 | 1.43 (0.99–2.00) |
Data are presented as n, unless otherwise indicated. SIR: standardised incidence ratio. #: p<0.05.