TABLE 1

Demographic characteristics of 42 individuals with miliary tuberculosis

Variable
Age years48.5 (29.0–65.0)
Age categories years
 16–257 (16.7)
 26–357 (16.7)
 36–455 (11.9)
 46–559 (21.4)
 >5514 (33.3)
Sex
 Female17 (40.5)
 Male25 (59.5)
Ethnicity
 White3 (7.1)
 Indian Subcontinent34 (80.9)
 Afro-Caribbean5 (11.9)
Place of birth
 UK3 (7.1)
 Foreign born39 (92.9)
Time since entry to the UK years#
 <17 (20.0)
 1–514 (40.0)
 6–105 (14.3)
 >109 (25.7)
HIV status
 Negative34 (89.5)
 Positive4 (10.5)
Monocyte:lymphocyte ratio+
 Pre-treatment0.47 (0.33–0.73)
 Post-treatment0.25 (0.16–0.27)
Assessment of CNS involvement
 Patients assessed for CNS involvement39 (92.9)
  Imaging of CNS§28 (71.8)
   Head CT performed14 (50.0)
    CT abnormal2 (14)
   Head MRI performed20 (71.4)
    MRI abnormal13 (65)
   Lumbar puncture performed§31 (79.5)
    Lumbar puncture abnormal5 (16.7)
Patients with CNS involvement and test outcome
 Total number of patients with CNS involvement§15 (38.5)
  Lumbar puncture performed in those with CNS involvement12 (80.0)
   Lumbar puncture sensitivity % (95% CI)41.7 (15.2–72.3)
  Head CT performed in those with CNS involvement n5
   Head CT sensitivity % (95% CI)40.0 (5.3–85.3)
  Head MRI performed in those with CNS involvement n14
   Head MRI sensitivity % (95% CI)92.9 (66.1–99.8)
  • Data are presented as n (%) or median (interquartile range), unless otherwise stated. CNS: central nervous system; CT: computed tomography; MRI: magnetic resonance imaging. #: data available for 35 patients; : four patients did not have a HIV test; +: data available for 23 patients; §: denominator is 39 patients.