TABLE 1

Phenotypic features of genotyped siblings having bronchial hyperresponsiveness in the Epidemiological study on the Genetics and Environment of Asthma (EGEA), Saguenay–Lac-Saint-Jean (SLSJ) asthma study and Southampton asthma family cohort (SOTON) asthma-ascertained families

EGEASLSJSOTON
Subjects304145382
Age years16.1 (15.2–17.0)20.3 (18.6–22.0)10.6 (8.0–13.8)
Females43.4 (132)52.4 (76)44.5 (170)
Asthma59.5 (181)95.2 (138)94.8 (362)
Age at asthma onset years7.4 (6.3–8.6)9.4 (7.7–11.0)4.4 (4.0–4.7)
Atopy76.0 (228)85.8 (121)77.5 (296)
ETS exposure57.9 (176)64.1 (93)29.8 (114)
  • Data are presented as n, mean (95% CI) or % (n). ETS: environmental tobacco smoke.