Characteristics of patients and multivariate regression analysis including CRB-65 criteria and mechanical ventilation on admission according to 3-day mortality
| Characteristic | Univariate analysis | Multivariate analysis | |||
| 3-day nonsurvivors | 3-day survivors | p-value | OR (95% CI) | p-value | |
| Patients n | 18 474 | 761 242 | |||
| Demographics | |||||
| Age years | 77.8±11.7 | 69.5±16.5 | <0.001 | ||
| Male sex | 11 189 (60.6) | 443 267 (58.2) | <0.001 | ||
| CRB-65 criteria | |||||
| Age ≥65 years | 16 063 (86.9) | 533 548 (70.1) | <0.001 | 2.43 (2.33–2.54) | <0.001 |
| Pneumonia-related confusion | 3973 (21.5) | 44 243 (5.8) | <0.001 | 3.48 (3.35–3.61) | <0.001 |
| Respiratory rate ≥30 breaths per min | 3819 (20.7) | 68 085 (8.9) | <0.001 | 2.28 (2.20–2.37) | <0.001 |
| Blood pressure <90/≤60 mmHg | 6610 (35.8) | 135 050 (17.7) | <0.001 | 2.40 (2.33–2.48) | <0.001 |
| CRB-65 score | 1.65±0.89 | 1.03±0.75 | <0.001 | ||
| 0 | 1146 (6.2) | 176 464 (23.2) | |||
| 1 | 7851 (42.5) | 414 839 (54.5) | |||
| 2 | 6365 (34.5) | 145 803 (19.2) | |||
| 3 | 2564 (13.9) | 22 063 (2.9) | |||
| 4 | 548 (3.0) | 2073 (0.3) | |||
| MV | |||||
| On admission | 940 (5.1) | 7671 (1) | <0.001 | 9.09 (8.46–9.76) | <0.001 |
| At all | 4296 (23.3) | 45 417 (6.0) | <0.001 | ||
| Invasive only | 2192 (11.9) | 12 358 (1.6) | |||
| Noninvasive only | 1342 (7.3) | 19 400 (2.5) | |||
| Both | 762 (4.1) | 13 659 (1.8) | |||
Data are presented as mean±sd or n (%), unless otherwise stated. MV: mechanical ventilation.