Prognostic outcomes for radiologically proven pneumonia in amoxicillin versus placebo group compared to those without pneumonia
| Amoxicillin | Placebo | Interaction term (95% CI) | p-value | Analysis | p-value | Missing n (%) | |
| Time to resolution of symptoms rated moderately bad days | |||||||
| Pneumonia present | 5 (2–9) | 11 (7–20) | 2.04 (1.10–3.80) | 0.024 | 2.20 (1.18–4.08)¶ | 0.013 | 8 (14.3) |
| Pneumonia absent | 6 (3–12) | 7 (4–13) | 1.05 (0.95–1.16) ¶ | 0.363 | 182 (9.7) | ||
| Symptom severity score on days 2–4 after consultation | |||||||
| Pneumonia present | 1.48±0.95 | 2.16±1.02 | −0.63 (−1.27–0.00) | 0.050 | −0.68 (−1.28–−0.08)+ | 0.027 | 10 (17.9) |
| Pneumonia absent | 1.82±1.05 | 1.87±1.08 | −0.05 (−0.15–0.06)+ | 0.365 | 232 (12.3) | ||
| Worsening of illness | |||||||
| Pneumonia present | 5/23 (22) | 15/33 (46) | 0.38 (0.11–1.30) | 0.125 | 0.33 (0.10–1.11)§ | 0.074 | 0 (0.0) |
| Pneumonia absent | 149/934 (16) | 160/895 (18) | 0.87 (0.68–1.11)§ | 0.272 | 0 (0.0) |
Data are presented as median (interquarile range (IQR)), mean±sd, or n/N (%) unless otherwise stated. #: interaction addresses the comparison of the effects of amoxicillin between those with and without pneumonia.¶: data presented as hazard ratio (95% CI); +: data presented as difference (95% CI); §: data presented as odds ratio (95% CI).