ALK FISH-positive patients# | ALK FISH-negative patients¶ | p-value | |
Patients | 140 | 400 | |
Age yrs | 62 (17–86) | 63 (30–90) | 0.003 |
Sex | 0.007 | ||
Males | 63 (45) | 233 (58) | |
Females | 77 (55) | 167 (42) | |
Tobacco habit | <0.0001 | ||
Former and current smokers | 22 and 9 (22)§ | 129 and 71 (50)§ | |
Nonsmokers | 64 (46) | 72 (18) | |
Light smokers+ | 11 (8) | 24 (6) | |
Not available | 34 (24) | 104 (26) | |
Tobacco consumption of former and current smokers pack-years | 40 (18–60) | 40 (18–160) | 0.15 |
Stages | 0.003 | ||
IA | 10 (7) | 45 (11) | |
IB | 5 (4) | 43 (11) | |
IIA | 9 (6) | 33 (8) | |
IIB | 4 (3) | 25 (6) | |
IIIA | 19 (13) | 68 (17) | |
IIIB | 5 (4) | 16 (4) | |
IV | 53 (38) | 90 (23) | |
Not available | 35 (25) | 80 (20) |
Data are presented as n, mean (range) or n (%), unless otherwise stated. #: ⩾15% of rearranged cells; ¶: <15% of rearranged cells; +: ⩽15 pack-years; §: total percentage of former and current smokers.