TABLE 3

Adjusted associations between characteristics of thoracentesis/pleural effusion and mortality among patients undergoing thoracentesis

Characteristic30-day mortality1-year mortality
Hazard ratio (95% CI)p-valueHazard ratio (95% CI)p-value
Thoracentesis#
 Bilateral2.58 (1.44–4.63)0.0022.32 (1.55–3.48)<0.001
Aetiology
 CHF0.33 (0.13–0.85)0.0210.28 (0.15–0.54)0.001
 Infectious disease0.20 (0.09–0.45)<0.0010.20 (0.12–0.33)<0.001
 Liver disease0.09 (0.01–0.71)0.0220.17 (0.07–0.45)0.003
 Multiple benign aetiologies0.43 (0.20–0.90)0.0240.36 (0.21–0.61)<0.001
 Paramalignant0.59 (0.28–1.25)0.1640.87 (0.54–1.40)0.568
 Renal disease0.24 (0.05–1.07)0.0610.37 (0.17–0.81)0.013
Covariates
 Age in years0.99 (0.97–1.01)0.4301.01 (0.97–1.02)0.361
 Male sex0.96 (0.58–1.60)0.8771.07 (0.77–1.40)0.686
 Nonwhite race0.63 (0.28–1.42)0.2620.98 (0.61–1.58)0.937
 Number of comorbidities1.21 (1.05–1.39)0.0091.19 (1.09–1.30)<0.001
  • CHF: congestive heart failure. #: referent to unilateral; : referent to malignant.