Incidence rates of community-acquired pneumonia (CAP), pneumococcal CAP, and CAP due to 7-valent pneumococcal conjugate vaccination (PCV7), additional PCV13 and other serotypes by study year
| Patient age years | Year 1, 2008–2009 | Year 2, 2009–2010 | Year 3, 2010–2011 | Year 4, 2011–2012 | Year 5, 2012–2013 | ||||||
| n | Incidence# (95% CI) | n | Incidence# (95% CI) | n | Incidence# (95% CI) | n | Incidence# (95% CI) | n | Incidence# (95% CI) | ||
| CAP | 506 | 90.7 (83.0–99.0) | 439 | 78.7 (71.5–86.4) | 359 | 64.4 (57.9–71.4) | 560 | 100.4 (92.3–109.1) | 365 | 65.4 (58.9–72.5) | |
| 16–24 | 16 | 14.0 (8.0–22.7) | 6 | 5.3 (1.9–11.4) | 11 | 9.6 (4.8–17.2) | 23 | 20.1 (12.8–30.2) | 15 | 13.1 (7.4–21.6) | |
| 25–44 | 50 | 27.9 (20.7–36.7) | 60 | 33.4 (25.5–43.0) | 51 | 28.4 (21.2–37.4) | 61 | 34.0 (26.0–43.7) | 49 | 27.3 (20.2–36.1) | |
| 45–64 | 97 | 59.7 (48.4–72.8) | 91 | 56.0 (45.1–68.7) | 82 | 50.4 (40.1–62.6) | 131 | 80.6 (67.4–95.6) | 95 | 58.4 (47.3–71.4) | |
| 65–74 | 113 | 201.4 (166.0–242.2) | 89 | 158.7 (127.4–195.2) | 77 | 137.2 (108.3–171.6) | 107 | 190.7 (156.3–230.5) | 77 | 137.2 (108.3–171.6) | |
| 75–84 | 129 | 360.3 (300.8–428.1) | 111 | 310.1 (255.1–373.4) | 91 | 254.2 (204.7–312.1) | 148 | 413.4 (349.5–485.6) | 88 | 245.8 (197.2–302.8) | |
| >85 | 101 | 1052.1 (856.9–1278.4) | 82 | 854.2 (679.3–1060.2) | 47 | 489.6 (359.7–651.0) | 90 | 937.5 (753.9–1152.3) | 41 | 427.1 (306.5–579.4) | |
| Pneumococcal CAP | 196 | 35.1 (30.4–40.4) | 150 | 26.9 (22.8–31.6) | 100 | 17.9 (14.6–21.8) | 92 | 16.5 (13.3–20.2) | 115 | 20.6 (17.0–24.8) | |
| 16–24 | 6 | 5.2 (1.9–11.4) | 4 | 3.5 (1.0–9.0) | 3 | 2.6 (0.5–7.7) | 3 | 2.6 (0.5–7.7) | 6 | 5.2 (1.9–11.4) | |
| 25–44 | 22 | 12.3 (7.7–18.6) | 26 | 14.5 (9.5–21.2) | 22 | 12.3 (7.7–18.6) | 10 | 5.6 (2.7–10.2) | 19 | 10.6 (6.4–16.5) | |
| 45–64 | 40 | 24.6 (17.6–33.5) | 31 | 19.1 (13.0–27.1) | 24 | 14.8 (9.5–22.0) | 20 | 12.3 (7.5–19.0) | 26 | 16.0 (10.4–23.4) | |
| 65–74 | 39 | 69.5 (49.4–95.0) | 28 | 49.9 (33.2–72.1) | 22 | 39.2 (24.6–59.4) | 20 | 35.6 (21.8–55.1) | 23 | 41.0 (26.0–61.5) | |
| 75–84 | 49 | 136.9 (101.3–181.0) | 34 | 95.0 (65.8–132.7) | 18 | 50.3 (29.8–79.5) | 24 | 67.0 (43.0–99.8) | 25 | 69.8 (45.2–103.1) | |
| >85 | 40 | 416.7 (297.7–567.4) | 27 | 281.2 (185.3–409.2) | 11 | 114.6 (57.2–205.0) | 15 | 156.2 (87.4–257.7) | 16 | 166.7 (95.3–270.7) | |
| PCV7 CAP | 62 | 11.1 (8.5–14.2) | 9 | 1.6 (0.7–3.1) | 8 | 1.4 (0.6–2.8) | 2 | 0.4 (0.0–1.3) | 13 | 2.3 (1.2–4.0) | |
| 16–24 | 0 | 0 | 1 | 0.9 (0.0–4.9) | 0 | 0 | 0 | 0 | 0 | 0 | |
| 25–44 | 4 | 2.2 (0.6–5.7) | 0 | 0 | 1 | 0.6 (0.0–3.1) | 0 | 0 | 3 | 1.7 (0.3–4.9) | |
| 45–64 | 12 | 7.4 (3.8–12.9) | 3 | 1.8 (0.4–5.4) | 2 | 1.2 (0.0–4.4) | 1 | 0.6 (0.0–3.4) | 1 | 0.6 (0.0–3.4) | |
| 65–74 | 15 | 26.7 (15.0–44.1) | 1 | 1.8 (0.0–9.9) | 3 | 5.3 (1.1–15.6) | 1 | 1.8 (0.0–9.9) | 4 | 7.1 (1.9–18.3) | |
| 75–84 | 14 | 39.1 (21.4–65.6) | 1 | 2.8 (0.1–15.6) | 1 | 2.8 (0.1–15.6) | 0 | 0 | 2 | 5.6 (0.7–20.2) | |
| >85 | 17 | 177.1 (103.2–283.5) | 3 | 31.2 (6.4–91.3) | 1 | 10.4 (0.3–58.0) | 0 | 0 | 3 | 31.2 (6.4–91.3) | |
| Additional PCV13 CAP | 59 | 10.6 (8.0–13.6) | 64 | 11.5 (8.8–14.6) | 45 | 8.1 (5.9–10.8) | 44 | 7.9 (5.7–10.6) | 35 | 6.3 (4.4–8.7) | |
| 16–24 | 1 | 0.9 (0.0–4.9) | 1 | 8.7 (4.2–16.1) | 2 | 1.7 (0.2–6.3) | 3 | 2.6 (0.5–7.7) | 3 | 2.6 (0.5–7.7) | |
| 25–44 | 9 | 5.0 (2.3–9.5) | 15 | 8.4 (4.7–13.8) | 13 | 7.2 (3.9–12.4) | 4 | 2.2 (0.6–5.7) | 6 | 3.3 (1.2–7.3) | |
| 45–64 | 10 | 6.2 (3.0–11.3) | 16 | 9.8 (5.6–16.0) | 11 | 6.7 (3.4–12.1) | 12 | 7.4 (3.8–12.9) | 9 | 5.5 (2.5–10.5) | |
| 65–74 | 13 | 23.2 (12.3–39.6) | 11 | 19.6 (9.8–35.1) | 10 | 17.8 (8.6–32.8) | 13 | 23.2 (12.3–39.6) | 7 | 12.5 (5.0–25.7) | |
| 75–84 | 16 | 44.7 (25.6–72.6) | 11 | 30.7 (15.3–55.0) | 4 | 11.2 (3.0–28.6) | 7 | 19.6 (7.9–40.3) | 8 | 22.3 (9.6–44.0) | |
| >85 | 10 | 104.2 (50.0–191.6) | 10 | 104.2 (50.0–191.6) | 5 | 52.1 (16.9–121.6) | 5 | 52.1 (16.9–121.6) | 2 | 20.8 (2.5–75.3) | |
| Other CAP | 24 | 4.3 (2.8–6.4) | 23 | 4.1 (2.6–6.2) | 15 | 2.7 (1.5–4.4) | 12 | 2.1 (1.1–3.8) | 21 | 3.8 (2.3–5.8) | |
| 16–24 | 0 | 0 | 1 | 0.9 (0.0–4.9) | 0 | 0 | 0 | 0 | 0 | 0 | |
| 25–44 | 7 | 3.9 (1.6–8.0) | 3 | 1.7 (0.3–4.9) | 2 | 1.1 (0.1–4.0) | 2 | 1.1 (0.1–4.0) | 4 | 2.2 (0.7–5.7) | |
| 45–64 | 7 | 4.3 (1.7–8.9) | 7 | 4.3 (1.7–8.9) | 4 | 2.5 (0.7–6.3) | 4 | 2.5 (0.7–6.3) | 7 | 4.3 (1.7–8.9) | |
| 65–74 | 2 | 3.6 (0.4–12.9) | 4 | 7.1 (1.9–18.3) | 4 | 7.1 (1.9–18.3) | 1 | 1.8 (0.0–9.9) | 5 | 8.9 (2.9–20.8) | |
| 75–84 | 6 | 16.8 (6.2–36.5) | 6 | 16.8 (6.2–36.5) | 4 | 11.2 (3.0–28.6) | 3 | 8.4 (1.7–24.5) | 3 | 8.4 (1.7–24.5) | |
| >85 | 2 | 20.8 (2.5–75.3) | 2 | 20.8 (2.5–75.3) | 1 | 10.4 (0.2–58.0) | 2 | 20.8 (2.5–75.3) | 2 | 20.8 (2.5–75.3) | |
PCV7 CAP: CAP due to serotypes included in PCV7; additional PCV13 CAP: CAP due to additional serotypes included in PCV13; other CAP: CAP due to “other” serotypes. #: per 100 000.