Patient characteristics for module 1: evaluation of the FPHN ItinérAIR-HTAP predictive equation using a REVEAL validation cohort
| ItinérAIR-HTAP#,¶ | REVEAL+ | |
| Subjects n | 190 | 292 |
| Age years n (%) | 52.5 (16.1) | 52.1 (16.2) |
| Female:male ratio | 1.7:1 | 3.6:1 |
| Diagnosis | ||
| Idiopathic PAH | 80.5 | 92.5 |
| Familial PAH | 6.3 | 4.1 |
| Anorexigen-APAH | 13.2 | 3.4 |
| Functional class at diagnosis | ||
| I/II | 17.4 | 22.1 |
| III | 68.4 | 64.2 |
| IV | 14.2 | 13.7 |
| 6MWD m | 311±115 | 322±138 |
| Haemodynamics | ||
| Mean RAP mmHg | 9±6 | 10±6 |
| Mean PAP mmHg | 54±13 | 52±13 |
| PCWP mmHg | 8±3 | 9±3 |
| Cardiac output L·min−1 | 3.9±1.3 | 4.1±1.4 |
| Cardiac index L·min−1·m−2 | 2.2±0.7 | 2.1±0.6 |
| PVR Wood units | 13.1±6.1 | 11.8±5.7 |
| PVR index Wood units·m−2 | 22.4±10.1 | 22.9±10.5 |
Data are presented as % or mean±sd, unless otherwise stated. FPHN: French Pulmonary Hypertension Network; REVEAL: Registry to Evaluate Early and Long-term PAH Disease Management; PAH: pulmonary arterial hypertension; APAH: associated with PAH; 6MWD: 6-min walking distance; RAP: right atrial pressure; PAP: pulmonary artery pressure; PCWP: pulmonary capillary wedge pressure; PVR: pulmonary vascular resistance. #: FPHN ItinérAIR-HTAP is the French registry used to develop the FPHN ItinérAIR-HTAP predictive equation; ¶: the cohort included incident patients (n=56) and patients diagnosed within 3 years of study initiation (n=134); +: with non-missing 6MWD and cardiac output data.