TABLE 5

Distribution of mutation type according to exposure to overall passive smoking for EGFR and KRAS

Never exposedEver exposedp-value
EGFR
 Mutation in exon 180 (0)3 (4)NC
 Mutation in exon 1927 (60)49 (60)
 Mutation in exon 202 (4)3 (4)
 Mutation in exon 2114 (31)24 (30)
 Double mutation in EGFR gene2 (4)2 (2)
 Missing1
KRAS
 Transition#2 (40)2 (18)0.547
 Transversion3 (60)9 (82)
 Missing11
  • Data are presented as n (%) or n, unless otherwise stated. EGFR: epidermal growth factor receptor; KRAS: Kirsten rat sarcoma viral oncogene homologue; NC: not computable. #: G13D, G12G or G12D; : G12V, G12R or G12A.