Main characteristics of the BioCAST population
| Lung cancer in never smokers (BioCAST) | Lung cancer in ever smokers# | ||||
| Men | Women | p-value | All | ||
| Total patients n | 384 | 6246 | |||
| Sex % | |||||
| Women | 319 (83) | 19 | |||
| Men | 65 (17) | 81 | |||
| Age | 66.6±13.0 | 70.5±11.7 | 0.016¶ | 69.8±12.0 | 65.5±11.3+ |
| <55 years | 12 (19) | 30 (9) | 0.033 | 42 (11) | |
| World region origin | |||||
| Missing data n | 7 | 41 | 48 | ||
| Europe | 51/58 (88) | 253/278 (91) | 0.468§ | 304/336 (91) | |
| Africa | 4/58 (7) | 12/278 (4) | 16/336 (5) | ||
| Asia | 1/58 (2) | 9/278 (3) | 10/336 (3) | ||
| Caribbean | 2/58 (3) | 4/278 (1) | 6/336 (2) | ||
| Education level | |||||
| Missing data n | 7 | 44 | 51 | ||
| High school and more | 34/58 (59) | 115/275 (42) | 0.037 | 149/333 (45) | |
| Secondary school | 13/58 (22) | 66/275 (24) | 79/333 (24) | ||
| Never schooled/primary school | 11/58 (19) | 94/275 (34) | 105/333 (32) | ||
| Body mass index kg·m−2 | 25.4±4.8 | 23.7±5.4 | 0.015ƒ | 24.2±5.5 | |
| Missing data n | 7 | 46 | 53 | ||
| Underweight/normal | 27/58 (47) | 165/273 (60) | 0.087 | 192/331 (58) | |
| Pre-obese | 24/58 (41) | 74/273 (27) | 98/331 (30) | ||
| Obese | 7/58 (12) | 34/273 (13) | 41/331 (12) | ||
| Alcohol intake (in standard glass per day) | |||||
| Missing data n | 7 | 43 | 50 | ||
| 0–1 | 49/58 (85) | 265/276 (96) | 0.003## | 314/334 (94) | |
| ≥2 | 9/58 (16) | 11/276 (4) | 20/334 (6) | ||
Data are presented as n (%), median±interquartile range or n/N available (%), unless otherwise stated. #: data from the KBP-CPHG study [14]; ¶: t-test; +: both smokers and never smokers (n=7051); not available for smokers only; §: computed between “European” and “non-European” categories; ƒ: Mann-Whitney U test; ##: Fisher's exact test; all others are Chi-squared tests (for categorical variables).