TABLE 1 Clinical, spirometric and plethysmographic characteristics
CharacteristicsTotal populationCOPDAbsence of COPD
Subjects338 (100)88 (26)250 (74)
Age years50 (46–53)52 (48–56)49 (46–53)
Females58 (17)13 (15)45 (18)
Low BMI# 36 (11)15 (17)21 (8)
Smoking duration years30 (27–35)34 (29–39)30 (27–34)
Smoking pack-years30 (25–38)34 (27–40)30 (25–37)
History of cannabis consumption117 (35)36 (41)81 (32)
History of IDU88 (26)32 (36)56 (22)
CD4+ cell count μL−1 571 (395–763)498 (345–707)594 (427–780)
Nadir CD4+ cell count μL−1 177 (76–260)158 (71–232)182 (83–267)
Nadir CD4+ cell count <200 μL−1 195 (58)54 (61)141 (56)
History of AIDS-defining complication 97 (29)31 (35)66 (26)
Known duration of HIV infection years 17 (10–22)19 (11–24)17 (10–21)
Duration of HIV treatment years 14 (7–16)13 (7–16)14 (7–16)
Last viral load <50 copies·mL−1 298 (88)78 (89)220 (88)
HCV infection 100 (30)35 (40)65 (26)
History of Pneumocystis pneumonia 28 (8)11 (13)17 (7)
FEV1 L 3.2 (2.6–3.7)2.5 (2.0–2.9)3.4 (2.9–3.8)
FEV1 % predicted 89 (76–98)71 (59–79)93 (86–101)
FEV1/FVC 0.74 (0.68–0.80)0.61 (0.54–0.66)0.77 (0.74–0.81)
TLC L 7.1 (6.2–7.9)7.5 (6.7–8.4)6.9 (6.1–7.7)
TLC % predicted 107 (97–116)114 (104–126)104 (96–112)
RV§ L 2.5 (2.1–3.0)3.1 (2.3–3.9)2.4 (2.0–2.8)
RV§ % predicted 119 (100–147)152 (108–175)114 (99–133)
RV/TLC§ 37 (32–42)41 (36–49)35 (31–40)
RV/TLC§ % predicted 108 (93–121)120 (101–139)104 (92–117)
D LCO ƒ,## % predicted 68 (59–83)62 (52–76)71 (62–86)
  • Data are presented as n (%) or median (interquartile range). COPD: chronic obstructive pulmonary disease; BMI: body mass index; IDU: intravenous drug use; HCV: hepatitis C virus; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; TLC: total lung capacity; RV: residual volume; D lco: diffusing capacity of the lung for carbon monoxide. #: <18.5 kg·m−2; : n = 305; §: n = 302; ƒ: corrected for haemoglobin; ##: n = 199.