TABLE 5

Univariate analysis of factors associated with mortality

Variablep-value
Males0.910
Current or ex-smoker0.162
Age >56.1 years0.139
Absence of systemic autoimmune symptoms0.017
Absence of auto-antibody0.013
No diagnosis of UCTD# or CTDs0.001
Diagnosis of cHP0.004
Duration of symptoms >22.5 months0.839
Digital clubbing0.067
FVC <65.2% predicted0.125
DLCO <50.0% predicted0.062
Alveolar lymphocytosis >20%0.019
Alveolar neutrophilia >5%0.090
No response to therapy<0.0001
  • UCTD: undifferentiated connective tissue disease; CTDs: connective tissue diseases; cHP: chronic hypersensitivity pneumonitis; FVC: forced vital capacity; DLCO: diffusing capacity of the lung for carbon monoxide. #: UCTD as defined by Kinder's criteria [5].