Mean AUC (95% CI) | p-value | Sensitivity | Specificity | +LR | −LR | |
Rhinovirus positive | ||||||
Acute infection# | 0.77 (0.07) | <0.001 | 73.0 | 96.0 | 18.25 | 0.28 |
Recovered¶ | 0.84 (0.06) | <0.001 | 84.0 | 75.9 | 3.49 | 0.21 |
Rhinovirus negative | ||||||
Acute infection# | 0.81 (0.05) | <0.001 | 75.6 | 71.4 | 2.64 | 0.34 |
Recovered¶ | 0.67 (0.06) | 0.005 | 62.9 | 65.6 | 1.83 | 0.57 |
Sensitivities, specificities, and positive (+LR) and negative likelihood ratios (−LR) are reported for the respective optimum cut-points. Symptomatic infection was defined as the presence of expiratory wheeze as assessed by auscultation. Asymptomatic infections were defined as children never experiencing respiratory symptoms severe enough to consult a general practitioner. Recovered infections were defined as children with confirmed wheeze who were tested again after resolution of their first symptomatic infection. AUC: area under the curve. #: symptomatic versus asymptomatic; ¶: ex-symptomatic versus asymptomatic.