TABLE 1 Baseline subject characteristics
Rhinovirus positiveRhinovirus negative
SymptomaticAsymptomaticSymptomaticAsymptomatic
Subjects n37264471
Females11 (31)14 (54)18 (41)33 (47)
Age at first visit months16.8±9.427.8±4.9**19.5±9.428.3±3.5**
Birth weight kg3.5±0.63.6±0.63.5±0.63.5±0.5
Prematurity1 (3)0 (0)0 (0)5 (7)
Breast milk fed31 (84)24 (92)35 (80)66 (93)
Parental asthma10 (27)2 (8)**14 (32)10 (14)**
Prenatal smoke exposure1 (3)1 (4)4 (9)3(4)
Environmental smoke exposure#4 (11)3 (12)7 (16)5 (7)
β2-agonist use23 (62)NA25 (57)NA
ICS use9 (24)NA11 (25)NA
PRAM severity2.5±2.0NA2.4±1.7NA
ACQ-based control14.6±7.3NA16.9±6.5NA
Time to recovery weeks28.3±14.3NA21.1±14.9NA
Positive PCRNANA33 (75)12 (17)**
Co-infection19 (51)3 (12)*12 (27)1 (1)*
  • Data are presented as n (%) or mean±sd, unless otherwise stated. Breastfed infants were breastfed at least during the first month of their life. Parental asthma was defined as a parent-reported doctor diagnosis of asthma in either parent. Prenatal smoke exposure was defined as smoking by or near the mother while she was pregnant. ICS: inhaled corticosteroid; PRAM: Pediatric Respiratory Assessment Measure; ACQ: Asthma Control Questionnaire; NA: not applicable. #: missing values (n=2) were replaced by the respective group mean. *: p<0.05 for comparison with symptomatic children; **: p<0.01 for comparison with symptomatic children.