TABLE 2 Symptoms, ventilation, metabolic data, diaphragm electromyogram (EMG) activity and neuroventilatory uncoupling at rest before cycle exercise and at end of exercise
Before exerciseEnd of exercise
Work W30 (20–47.5)
Exercise time min10.7 (8.1–16.8)
Borg breathlessness score0 (0–0.5)8 (5–10)
Borg leg fatigue score0 (0–0)5 (4.25–8.75)
VE L·min−110 (8.9– 0.7)23.7 (18.5–29.4)
Inspiratory capacity L1.8 (1.5–1.9)1.39 (1.0–1.98)
Change in inspiratory capacity pre/post exercise mL270.0 (100.0–440.0)
VO2 mL·kg−1··min−13.5 (3.2–4.3)12.8 (9.8–14.1)
VCO2 mL·kg·min−13.6 (3.0–4.0)12.3 (10.0–15.3)
Respiratory exchange ratio1.0 (0.9–1.1)1.0 (0.92–1.06)
Oxygen saturation %96.2 (95.1–97.0)92.3 (90.9–94.5)
ti/ttot%34.1 (32.2–35.3)33.7 (29.2–34.4)
Respiratory rate min−121.0 (14–23.7)28.8 (26.9–34.4)
VT mL476.6 (426.6–607.2)789.1 (645.4–1008.0)
VT%VCpred %15.7 (13.1–16.8)23.6 (20.4–33.7)
EMGdi%max16.9 (14.3–20.6)73.3 (60.6–77.4)
EMGdi%max/VT%VCpred1.05 (0.94–1.31)2.86 (2.06–3.83)
  • Data are presented as mean (IQR). VE: minute ventilation; VO2: oxygen uptake, VCO2: carbon dioxide production; ti/ttot: ratio of inspiratory time to total breath duration; VT: tidal volume; VT%VCpred: tidal volume expressed as a percentage of predicted vital capacity; EMGdi%max: mean root mean square (RMS) diaphragm electromyogram (EMGdi) activity per breath, expressed as a percentage of maximum RMS EMGdi recorded during maximal inspiratory manoeuvres.