TABLE 1 Number of observed cancers and standardised cancer incidence ratios (SIRs) in all sarcoidosis patients and those treated with an immunosuppressant
All sarcoidosis patients#Sarcoidosis patients treated with immunosuppressive agents
0 to <3 months3 months to <3 years3-10 years>10 yearsOverall3–10 years>10 years
All+1499.1 (7.7–10.7)2431.5 (1.3–1.7)4191.2 (1.1–1.3)4921.1 (1.0–1.2)13031.3 (1.3–1.4)741.2 (0.9–1.5)271.3 (0.9–2.0)
 Tonsils2063.8 (39.0–98.6)113.5 (1.7–6.2)132.1 (1.1–3.6)71.3 (0.5–2.6)513.4 (2.5–4.4)00
 Stomach010.4 (0.00–2.1)61.1 (0.4–2.5)71.1 (0.4–2.2)141.0 (0.5–1.6)11.2 (0.0–6.8)0
 Colon65.8 (2.1–12.6)111.1 (0.5–1.9)371.7 (1.2–2.4)281.0 (0.7–1.4)831.4 (1.1–1.7)61.6 (0.6–3.6)21.6 (0.2–5.9)
 Rectum47.1 (1.9–18.1)40.7 (0.2–1.8)131.1 (0.6–1.9)191.2 (0.7–1.9)401.2 (0.9–1.6)21.0 (0.1–3.5)11.5 (0.0–8.2)
 Pancreas38.4 (1.7–24.6)10.3 (0.0–1.6)81.1 (0.5–2.2)101.0 (0.5–1.9)221.1 (0.7–1.6)10.8 (0.0–4.4)0
 Gall bladder/biliary tract011.2 (0.0–6.4)42.4 (0.6–6.0)62.9 (1.1–6.3)112.3 (1.2–4.2)0111.1 (0.3–61.7)
 Lungs3218.7 (12.8–26.3)251.5 (0.9–2.1)310.9 (0.6–1.3)260.6 (0.4–0.8)1141.1 (0.9–1.4)111.8 (0.9–3.2)21.0 (0.1–3.6)
 Breast31.4 (0.3–4.1)190.9 (0.5–1.3)420.9 (0.6–1.2)541.0 (0.7–1.3)1180.9 (0.8–1.1)60.8 (0.3–1.7)20.8 (0.1–3.0)
 Malignant melanoma23.2 (0.4–11.4)40.6 (0.2–1.5)100.7 (0.3–1.3)150.9 (0.5–1.5)300.8 (0.5–1.2)31.1 (0.2–3.3)22.5 (0.3–8.9)
 Basal cell carcinoma51.9 (0.6–4.4)531.9 (1.4–2.5)861.4 (1.1–1.8)1071.2 (1.0–1.5)2511.4 (1.2–1.6)151.2 (0.7–2.0)51.2 (0.4–2.7)
 Squamous cell skin cancer12.6 (0.1–14.3)123.0 (1.6–5.3)202.4 (1.5–3.7)423.2 (2.3–4.3)752.9 (2.3–3.6)52.6 (0.9–6.2)11.5 (0.0–8.2)
 Cervix uteri13.3 (0.1–18.2)41.3 (0.3–3.3)61.0 (0.4–2.2)51.1 (0.3–2.5)161.1 (0.7–1.9)11.3 (0.0–7.4)0
 Uterus12.6 (0.1–14.7)51.3 (0.4–3.0)70.9 (0.4–1.9)111.2 (0.6–2.2)241.1 (0.7–1.7)10.9 (0.0–4.9)12.7 (0.1–14.9)
 Ovary13.1 (0.1–17.2)20.6(0.1–2.2)71.1 (0.4–2.2)101.4 (0.7–2.6)201.2 (0.7–1.8)11.1 (0.0–6.2)0
 Prostate55.2 (1.7–12.0)101.0 (0.5–1.9)211.7 (0.7–1.6)411.2 (0.8–1.6)771.2 (0.9–1.5)51.0 (0.3–2.3)42.3 (0.6–6.0)
 Testes010.4 (0.0–2.1)71.5 (0.6–3.1)41.3 (0.3–3.3)121.1 (0.6–2.0)22.7 (0.3–9.7)0
 Kidney311.1 (2.3–32.4)41.5 (0.4–3.8)61.1 (0.4–2.3)91.2 (0.5–2.3)221.4 (0.8–2.1)11.0 (0.0–5.4)13.0 (0.1–16.5)
 Bladder25.9 (0.7–21.4)30.9 (0.2–2.6)71.1 (0.4–2.2)40.5 (0.1–1.1)160.8 (0.5–1.4)21.7 (0.2–6.2)12.7 (0.1–14.9)
 Brain613.1 (4.8–28.5)163.4 (1.9–5.5)121.3 (0.7–2.2)60.6 (0.2–1.2)401.6 (1.1–2.1)21.2 (0.1–4.4)0
 Hodgkin lymphoma9107 (49.0–203)67.2 (2.6–15.7)42.7 (0.7–6.9)0195.3 (3.2–8.2)28.8 (1.1–31.8)0
 Non-Hodgkin lymphoma2357.1 (36.2–85.7)215.1 (3.2–7.8)182.1 (1.2–3.3)181.6 (1.0–2.6)803.3 (2.6–4.1)21.3 (0.2–4.7)12.0 (0.1–11.3)
 Myeloid leukaemia321.5 (4.4–62.8)53.6 (1.2–8.3)41.4 (0.4–3.7)20.6 (0.1–2.3)141.9 (1.0–3.1)00
 Multiple myeloma537.4 (12.1–87.1)43.0 (0.8–7.6)62.2 (0.8–4.7)51.4 (0.4–3.2)202.5 (1.5–3.9)12.1 (0.1–11.7)0
  • Data are presented as observed number or SIR (95% CI). #: n = 12 890; : n = 3115; +: the site specific numbers do not add up to the total number because not all cancer sites are presented.