Table 1. Comparison of Geometric Mean Ratios (GMR) Between Treatments | |||||
Treatment Ratio | Analyte | AUC0-12 GMR (90% CI) | Cmax GMR (90% CI) | ||
BGF 320/14.4/9.6 µg / Symbicort 320/9 µg | BD | 1.15 (1.06, 1.24) | 1.02 (0.91, 1.14) | ||
BGF 320/14.4/9.6 µg / GFF 14.4/9.6 µg | FF | 1.04 (0.97, 1.11) | 1.11 (1.01, 1.22) | ||
BGF 320/14.4/9.6 µg / GFF 14.4/9.6 µg | GP* | 1.01 (0.86, 1.18) | 1.15 (0.99, 1.34) | ||
*GP bioequivalence assessed using wider bounds due to high variability. |