| What is known? |
| Traditional risk factors for cardiovascular disease in adults are well established |
| Emerging evidence |
| Adverse intrauterine environments increase life-long risks of cardiovascular disease |
| Biomarkers of vascular stiffness and endothelial dysfunction in early life predict future cardiovascular disease |
| Speculation |
| Environmental exposures in early life increase the risk of cardiovascular disease more than similar exposures in later life |