Table 1– Baseline demographics presented for study population#
VariableResult
Age years54.15±13.50
Sex
 Males83 (43.5)
 Females108 (56.5)
Age when diagnosed years
 0–516 (8.4)
 >5175 (91.6)
BTS treatment step
 257 (29.84)
 3111 (58.12)
 423 (12.04)
Smoking pack-years0 (0–4)
Height cm169.24±9.89
Mass kg81.14±17.31
BMI kg·m−228.27±5.36
BDP-equivalent daily dose μg·day−1400 (200–1000)
FEV1 L2.68±0.85
FEV1 % predicted89.85±19.15
FVC L3.65±1.00
FVC % predicted99.81±16.87
Airway hyperresponsiveness PC20 mg·mL−1 geometric mean (95% CI)8.02 (6.31–10.17)
Blood IgE kIU·L−191.5 (28.50–253.50)
Blood eosinophils ×109 cells·L−10.20 (0.12–0.32)
Sputum eosinophils %0.80 (0.25–4.75)
Sputum neutrophils %64.75 (42.25–84.00)
ACQ-5 score0.60 (0.20–1.00)
  • Data are presented as mean±sd, n (%) or median (interquartile range), unless otherwise stated. BTS: British Thoracic Society; BMI: body mass index; BDP: beclomethasone dipropionate; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; PC20: provocative concentration of methacholine producing a 20% fall in FEV1; ACQ-5: five-item Asthma Control Questionnaire. #: n=191; : QVAR (Teva, Castleford, UK), 2:1 BDP; Flixotide (GlaxoSmithKline, London, UK), 2:1 BDP; budesonide, 1:1 BDP.