TABLE 2 Physical symptoms in lung cancer and their qualifying guidance for therapeutic interventions

Physical symptoms	References
Tumour-related
Dyspnoea	[27, 29, 30]
Pain	[27, 28, 31]
Superior vena cava syndrome	[27–29]
Endotracheobronchial obstruction	[27–29]
Haemoptysis	[27–29]
Tracheobronchial-oesophageal fistula	[27, 28]
Pleural effusion	[27–29]
Hoarseness	[29]
Cough	[27, 29, 30, 32]
Fatigue	[27, 30]
Bone metastases	[27, 29, 33, 34]
Brain metastases	[27, 29]
Spinal cord compression	[27, 29, 35]
Cachexia/muscle wasting	[27, 28, 30]
Venous thromboembolic disease	[27, 36–39]
Hypercalcaemia	[28, 29]
Hyponatraemia/SIADH	[28, 40, 41]
Therapy-related
Nausea/vomiting	[28, 42, 43]
Anaemia	[28, 44, 45]
Neutropenia	[28, 46–49]
Thrombopenia	[50]
Radiotherapy-induced pneumonitis/pulmonary fibrosis	[28, 51]
Dermatitis	[28, 51]
Mucositis	[28, 51–53]
Post-thoracotomy pain	[54]