Study | Subjects n | nNO cut-off nL·min−1 | Sensitivity % | Specificity % |
Mateos-Corral et al. [26], 2011# | 44 | 60.8 | 100 | 100 |
Narang et al. [7], 2002 | 157 | 25 | 75 | 96 |
62.5 | 97 | 90 | ||
Horvath et al. [8], 2003 | 102 | 46.8 | 93 | 95 |
Corbelli et al. [10], 2004 | 34 | 126 | 94 | 88 |
Marthin and Nielsen [25], 2011 | 94 | Breath hold 52.5 | 91.1 | 100 |
Oral exhalation 72.6 | 94.3 | 100 | ||
Tidal breathing 47.4 | 94.4 | 100 | ||
Leigh et al. [19], 2013 | 227 | 77 | 98 | >99.9 |
Marthin and Nielsen [17], 2013 | 57 | 78.6 | 100 | 100 |
Harris et al. [32], 2014 | 47 | 38 | 100 | 95 |
Boon et al. [31], 2014 | 226 | 90 | 89.5 | 87.3 |
nNO: nasal nitric oxide; PCD: primary ciliary dyskinesia. #: bronchiectasis patients included in healthy control group.