Table 3– Comparison of physiological responses to the 6-min walk test (6MWT) and cardiopulmonary exercise test (CPET)#
First author [ref.]Subjects nPatient groupVO2peak mL·min−1HR peak bpmVCO2peak mL·min−1RERVEpeak L·min−1
6MWTCPET6MWTCPET6MWTCPET6MWTCPET6MWTCPET
Troosters [21]20COPD1400±2901410±180126±13130±131300±3101450±180*0.92±0.071.04±0.08*42±847±8*
Satake [34]12COPD14.5±2.113.9±3.6109±19112±1612.56±2.0214.55±5.4526±729±11
Turner [35]20COPD126±15124±12
Luxton [38]22COPD1394±4041383±437121±9128±221069±3781208±434*44±1348±15*
Hill [37]50COPD119±15123±17
Hill [48]26COPD1168±3441186±314128±17128±191009±2701173±350*0.87±0.110.99±0.17*41±1748±17*
Blanco [49]13ILD14±215±2112±19125±2*0.94±0.11.02±0.07*46.4±15.153.8±14.6*
Holland [41]14ILD15.1±3.517.5±2.6¶,*
Deboeck [44]20PAH14.2±2.712.9±3.1119±17.9135±17.9881±2901024±380¶,*0.90±0.091.15±0.09*46.0±14.853.6±17.4*
Blanco [49]14PAH16±616±6142±24146±231.00±0.121.17±0.08¶,*52.2±15.268.8±21.2*
  • Data are presented as mean±sd, unless otherwise stated. VO2peak: peak oxygen uptake; HR: heart rate; VCO2peak: peak carbon dioxide production; RER: respiratory exchange ratio; VEpeak: peak ventilation; COPD: chronic obstructive pulmonary disease; ILD: interstitial lung disease; PAH: pulmonary arterial hypertension. #: incremental cycle ergometer test; : data given in mL·kg−1·min−1. *: p<0.05 versus 6MWT data.