Table 2– Relationship between 6-min walking distance and peak oxygen uptake (VO2peak) or peak work in chronic respiratory disease
First author [ref.]DiagnosisSubjects nVO2peakPeak work
Pearson’s rSpearman’s rhoPearson’s rSpearman’s rho
Wijkstra [30]COPD400.81
Rejeski [17]COPD2090.64
Chuang [31]COPD270.40
Oga [32]COPD360.640.64
Carter [33]COPD1240.540.59
Satake [34]COPD120.64
Turner [35]COPD200.730.83
Starobin [36]COPD500.58
Hill [37]COPD500.630.75
Luxton [38]COPD220.63
Díaz [39]COPD810.78
Kozu [11]COPD450.800.80
Sillen [40]COPD29060.67
Eaton [12]IPF290.78
Kozu [11]IPF350.80
Holland [41]ILD140.93
Dale [42]Asbestos-related pleural disease250.530.58
Miyamoto [43]PAH270.70
Deboeck [44]PAH200.48
Fowler [45]EIPAH170.72
Baldi [46]LAM400.55
Cahalin [5]End-stage lung disease, pre transplant300.73
Ross [47]Mixed chronic lung diseases, many pre transplant480.59
  • COPD: chronic obstructive pulmonary disease; IPF: idiopathic pulmonary fibrosis; ILD: interstitial lung disease; PAH: pulmonary arterial hypertension; EIPAH: exercise-induced PAH; LAM: lymphangioleiomyomatosis.