Table 2– Prevalence of depressive symptoms/disorders in chronic obstructive pulmonary disease (COPD) patients reported in studies published from 2011 to 2013
First author [ref.]Assessment toolsPatientsPrevalence of depression %
De [22]PHQ-9100 consecutively recruited Indian patients with stable COPD72
Hayashi [23]HADS-D80 outpatients and 51 inpatients suffering from stable COPD in Japan40.5
Goodwin [24]CIDI diagnosis of major depression147 COPD patients (self report) in the USA24.8
Joo [25]Standardised questionnaires on comorbidities associated with COPD354 COPD patients (subsample of 9744 subjects from the Korean population)COPD: 18.7; non-COPD: 17.4
Loerbroks [26]GDS-15 sum score ≥4 points7995 COPD patients from a large population sample from southern China22.9
Lou [27]HADS-D ≥8 points1100 outpatients with COPD from China and 1100 healthy controlsCOPD: 35.7; controls: 7.2
Marinho [28]GDS-1540 elderly COPD patients from Brazil22.5
Obradovic [29]HDRS40 COPD patients from Serbia20.0
Schnell [30]Physicians’ lifetime diagnosis of depression995 COPD patients (aged ≥45 years) from the USA20.6
Arimura [31]CES-D score ≥10 points52 consecutively recruited and clinically stable COPD patients in the pulmonary departments of five hospitals in Japan29
Horita [32]SF-GDS ≥6 points84 consecutive, stable COPD outpatients in a Japanese community hospital38.1
Iguchi [33]Japanese version of the CES-D sum score ≥16 points74 COPD patients from long-term Japanese inpatient rehabilitation facilities48.6
Lee [34]PHQ-9 ≥10 points803 COPD inpatients from Korea23.8
Papaioannou [35]BDI-I sum score ≥19 points230 consecutive COPD inpatients in departments of respiratory medicine in two tertiary hospitals in Greece39.6
Qian [36]Clinical ICD-9-CM diagnoses of depressive disorders75 699 US beneficiaries# (minimum age 65 years) with a diagnosis of COPD21.6
Sharma [37]Global Mental Health Assessment Tool – Primary Care and General Health version52 consecutive patients with stable COPD attending a respiratory disease clinic in Northern IndiaCOPD: 19.2; controls: 3.4
Warmenhoven [38]General practitioners’ lifetime diagnosis of depressive disorders982 Dutch patients with COPD, cardiovascular disease and cancer in the last phase of their lives8.2
Zhang [39]Face-to-face questionnaire7597 COPD patients from China28.3
  • PHQ-9: patient health questionnaire-9; HADS-D: hospital anxiety and depression scale depression subscale; CIDI: composite international diagnostic interview; GDS-15: geriatric depression scale 15-item version; HDRS: Hamilton depression rating scale; CES-D: Center for Epidemiologic Studies depression scale; SF-GDS: short-form geriatric depression scale; BDI-I: Beck’s depression inventory I; ICD-9-CM: international classification of diseases, 9th revision, clinical modification. #: persons enrolled in Medicare parts A, B and D in the USA.