Lung function, rescue medication use and SGRQ change from baseline
| QVA149 N=119 | TIO N=39 | |
| Pre-dose FEV1 (mL) | ||
| Wk12 | 209 (172.5) | 139 (156.2) |
| Wk24 | 198 (173.5) | 115 (140.0) |
| Wk52 | 189 (176.2) | 52 (168.8) |
| Inspiratory capacity (mL) | ||
| Wk12 | 130 (316.3) | 79 (350.2) |
| Wk24 | 130 (276.1) | –14 (388.4) |
| Wk52 | 93 (339.6) | 81 (481.8) |
| Rescue medication use (puffs/day) | ||
| Wk52 | –0.6 (1.11) | –0.2 (0.84) |
| SGRQ change | ||
| Wk12 | –4.5 (10.91) | –2.7 (7.84) |
| Wk24 | –4.5 (11.70) | –0.3 (8.16) |
| Wk52 | –2.9 (10.99) | –0.6 (9.92) |
All values in mean (SD)