Model | Subjects n | Q1 OR | Q2 | Q3 | Q4 | p-value |
AHI or ODI entered separately | 10 494 | |||||
AHI | ||||||
Model 0 | 11 911 | 1.00 | 2.02 (1.81–2.26) | 2.82 (2.52–3.14) | 3.96 (3.54–4.42) | <0.0001 |
Model 1 | 10 949 | 1.00 | 1.29 (1.13–1.48) | 1.40 (1.22–1.60) | 1.52 (1.31–1.76) | <0.0001 |
Model 2 | 11 487 | 1.00 | 1.31 (1.15–1.49) | 1.41 (1.23–1.60) | 1.51 (1.31–1.73) | <0.0001 |
ODI | ||||||
Model 0 | 11 911 | 1.00 | 2.30 (2.05–2.58) | 3.48 (3.11–3.90) | 4.86 (4.34–5.45) | <0.0001 |
Model 1 | 10 949 | 1.00 | 1.49 (1.30–1.70) | 1.73 (1.51–1.98) | 1.87 (1.62–2.17) | <0.0001 |
Model 2 | 11 487 | 1.00 | 1.48 (1.30–1.69) | 1.73 (1.52–1.98) | 1.86 (1.62–2.14) | <0.0001 |
Both AHI and ODI entered simultaneously | 8925 | |||||
AHI | ||||||
Model 0 | 11 911 | 1.00 | 1.27 (1.11–1.45) | 1.38 (1.19–1.60) | 1.50 (1.25–1.80) | <0.0001 |
Model 1 | 10 949 | 1.00 | 1.01 (0.87–1.17) | 0.95 (0.79–1.13) | 0.92 (0.74–1.15) | 0.3054 |
Model 2 | 11 487 | 1.00 | 1.02 (0.88–1.18) | 0.95 (0.80–1.13) | 0.90 (0.73–1.12) | 0.2363 |
ODI | ||||||
Model 0 | 11 911 | 1.00 | 2.03 (1.79–2.31) | 2.77 (2.38–3.22) | 3.56 (2.96–4.28) | <0.0001 |
Model 1 | 10 949 | 1.00 | 1.49 (1.28–1.73) | 1.79 (1.49–2.13) | 2.01 (1.61–2.51) | <0.0001 |
Model 2 | 11 487 | 1.00 | 1.48 (1.28–1.71) | 1.79 (1.51–2.13) | 2.03 (1.64–2.52) | <0.0001 |
Data are presented as OR (95% CI) unless otherwise stated. p-values are for linear trend across quartiles. Model 0: unadjusted; model 1: full model included the covariates age, sex, body mass index, waist/hip ratio, neck circumference, type 2 diabetes, dyslipidaemia, chronic obstructive pulmonary disease, smoking status, Epworth Sleepiness Scale (ESS) score, type of sleep study and sleep disordered breathing variables (i.e. quartiles of AHI or quartiles of ODI) entered separately or simultaneously into model; model 2: parsimonious model excluded from the full model the covariates waist/hip ratio, ESS score, chronic obstructive pulmonary disease and current smoking status.