| Treatment difference, QVA149 vs. SFC | ||||
| Parameter | Pts with LABA/ICS prior to baseline (n=122) | Overall pt population (N=522) | ||
| Wk 12 | Wk 26 | Wk 12 | Wk 26 | |
| FEV1 AUC0-12h, mL | 180(34)* | 160(38)* | 120(16)* | 140(19)* |
| Pre-dose trough FEV1, mL | 140(35)* | 150(40)* | 90(17)* | 100(19)* |
| Rescue medication use, puffs/day | -0.56(0.34) | -0.71(0.34)# | -0.28(0.16) | -0.39(0.17)# |
*p<0.001; #p<0.05