Clinical and haemodynamic variables at baseline and after oral ambrisentan therapy.
| Basal | Follow-up | p | ||
| WHO FC | 2.8±0.4 | 2.5±0.5 | 0.0027 | |
| 6MWD (m) | 322±66 | 350±62 | 0.00005 | |
| proBNP (pg/ml) | 588±535 | 392±315 | 0.008 | |
| Heart catheterization | mPAP (mmHg) | 50±17 | 49±16 | ns |
| CI (L/m/m2) | 2.4±0.5 | 2.7±0.4 | 0.0001 | |
| PVR (WU) | 10±6 | 8±4 | 0.007 |
FC, functional class; 6MWD, 6-minute walk distance; mPAP, mean pulmonary arterial pressure; CI, Cardiac Index; PVR, pulmonary vascular resistance.