Change from baseline

 Aclidinium 400 µg BIDPlaceboΔ
Adjusted LS mean (95% CI), Week 3
Endurance time, s68.3 (31.1, 105.6)9.8 (-27.8, 47.4)58.5* (9.0, 108.0)
Dyspnoea, units-0.48 (-0.87, -0.09)0.15 (-0.25, 0.54)-0.63* (-1.11, -0.14)
dIC, mL
At rest140 (78, 202)-36 (-98, 26)176‡ (92, 260)
Isotime117 (58, 0.176)-38 (-97, 21)155† (76, 234)
Peak119 (62, 175)-42 (-98, 14)161‡ (87, 235)
Mean over 1 week
Daily physical activity
Active energy consumption, kcal22-3355*
Step count, steps296-163459
Moderate activity, mins4.2-5.910.0*
  • p<0.05, †p<0.001, ‡p<0.0001