Table 1: Summary of mean BA and HPLC assay results (MIU) for each nebulizer/breathing pattern combination.

 I-nebLCSLCP
Breathing patternBAHPLCBAHPLCBAHPLC
A (I:E ratio 1:1, PIF 23.1 L/min, 15 BPM)0.2800.2770.2530.2610.2910.277
B (I:E ratio 1:2, PIF 23.1 L/min, 10 BPM)0.2580.2640.2110.2210.2070.206
C (I:E ratio 1:3, PIF 21.5 L/min, 7 BPM)0.2430.2580.1730.1600.1610.147
D (I:E ratio 1:4, PIF 23.1 L/min, 6 BPM)0.3060.2700.1510.1410.1550.144
  • I:E ratio=inhalation:exhalation ratio; PIF=peak inspiratory flow rate; BPM=breaths per minute.