Group 1 | Group 2 | |||
Gene expression profile | Ressembles normal lung | "Proliferative" and "invasive" gene clusters | ||
p-value | ||||
Smoking status | 0.01 | |||
Never smoker | 35 (61%) | 28 (50%) | ||
Ever smoker | 22 | 28 | ||
Lepidic component | 0.00005 | |||
Yes | 31 (54%) | 12 (21%) | ||
No | 26 | 34 | ||
EGFR mutation | 0.0002 | |||
Yes | 32 (56%) | 16 (30%) | ||
No | 25 | 38 | ||
KRAS mutation | 0.02 | |||
Yes | 4 (7%) | 14 (25%) | ||
No | 53 | 41 |