[table1]
| Tobra | Placebo | |
| n | 20 | 24 |
| n (ITT 1) | 11 | 21 |
| n (PP) | 6 | 14 |
| age (yrs) | 65.5±10.1 | 63.9±8.8 |
| Hospitalisations in the period of study (n) | 4.3±2.6 | 2.5±1.9 |
| Time to first hospitalisation (days) | 104±38 | 173±26 |
| 6 MWD (m) study entry | 398 | 380 |
| 6 MWD (m) end of study | 272 | 328 |