| Blood eosinophils <400 cells per mm3, sputum eosinophils <3%# | Blood eosinophils <400 cells per mm3, sputum eosinophils ≥3% | Blood eosinophils ≥400 cells per mm3, sputum eosinophils <3% | Blood eosinophils ≥400 cells per mm3, sputum eosinophils ≥3% | |
| IgE kU·L−1 | 87 (1–7338) | 211 (3–6785)*** | 180 (13–2329)* | 225 (1–17183)*** |
| Blood eosinophils % | 1.7 (0–5.4) | 3.2 (0–7)*** | 6 (0.3–15)*** | 8 (0.4–30)*** |
| Blood eosinophils per mm3 | 140 (0–380) | 250 (0–390)*** | 490 (400–1220)*** | 590 (400–3220)*** |
| Blood neutrophils % | 59 (27–82) | 57 (34–91) | 57 (41–76) | 52 (32–67)*** |
| Blood neutrophils per mm3 | 4180 (76–11 080) | 4370 (2290–15 410) | 5040 (1760–10 010) | 3965 (1820–8670) |
| Sputum eosinophils % | 0.3 (0–2.9) | 9 (3–79)*** | 0.6 (0–2.8) | 26 (3.2–94)*** |
| Sputum eosinophils per mm3 | 2.7 (0–1020) | 70 (6–5226)*** | 4.8 (0–1796) | 287 (5–33 375)*** |
| Sputum neutrophils % | 58 (0–100) | 39 (0–90)*** | 57 (0.2–99) | 30 (0.2–91)*** |
| Sputum neutrophils per mm3 | 422 (0–73 440) | 334 (1–9588) | 560 (14–160 974) | 259 (1–15 441) |
| Fibrinogen g·L−1 | 3.2 (1.9–10) | 3 (2–6) | 3.3 (2.6–5) | 3.4 (2.2–7) |
| CRP mg·L−1 | 1.7 (0.2–10) | 2 (0.2–14) | 1.4 (0.5–4) | 1.6 (0.2–13) |
| FeNO ppb | 17 (0–192) | 37 (2–222)*** | 32 (5–93)** | 77 (11–247)*** |
Data are presented as median (range). CRP: C-reactive protein; FeNO: exhaled nitric oxide. #: comparator group. *: p<0.05; **: p<0.01; ***: p<0.001.