Table*
| Plasma | Induced sputum | ||||
| 32.5mg (n=12) | 48.75mg (n=12) | 32.5mg (n=11) | 48.75mg (n=11) | ||
| AUC | mg•h/l | 0.600/16.0# | 0.901/16.2# | 552/119.3§ | 505/132.5§ |
| Cmax | mg/l | 0.114/26.8 | 0.183/26.3 | 409/89.9 | 454/141.3 |
| t½ | h | 6.00/23.2 | 4.99/17.9 | - | - |
| tmaxII | h | 0.875 | 1.00 | 0.550 | 0.583 |
*Geometric means/%CV; #AUC(0–∞); §AUC(0–tlast); IImedian