Enzyme and S1P receptor gene expression levels.

	NS n=13	S n=12	COPD n=23
SPHK1	1172±426	2253±854	1317±445
SPHK2	352±88	51±122	2808±1155
S1PR1	16±12	51±19	56±40
S1PR2	526±118	1463±268*	1545±320*
S1PR3	86±69	21±15	216±180
S1PR4	251±83	186±48	393±80
S1PR5	1±0	3±2	6±2

Table 1: Data are mean±SEM of % ratio gene:HPRT1; *p<0.05