Table 2– Clinical parameters, serum inflammatory cytokine concentrations, and neutrophil extracellular traps (NETs) length in bronchial aspirates at each time point
ParameterDay
013–56–8
WBC per μL13050 (9980–17880)10560 (8060–21130)8630 (7590–10450)10340 (7490–11900)
PLT ×103 per μL147 (123–191)137 (97–149)142 (95–219)211 (136–218)
CRP mg·dL−11.8 (0.4–21.6)8.6 (4.7–22.3)4 (2.8–12.6)6.3 (2.3–7.2)
D-dimer ng·mL−14 (2.2–22.7)3.7 (1.4–15.0)8.2 (4.3–13.6)6.4 (2.8–8.6)
Lactate mg·dL−139 (17–57)21 (9–26)11 (9–15)13.5 (7.8–18.5)
PCT ng·mL−10.7 (0.4–9.2)3.6 (1.8–16.4)2.2 (0.7–3.0)0.8 (0.1–1.1)
TNF-α pg·mL−117.3 (9.2–28.0)9.4 (7.4–17.9)10.9 (8.5–16.3)10 (7.7–14.8)
IL-6 pg·mL−1184 (85–910)82.8 (34.9–710.5)113.3 (22.0–288.3)82.7 (11.1–203.0)
IL-8 pg·mL−1118 (51.7–229.0)41.6 (24.5–151.8)47.6 (32.5–81.4)43.3 (22.4–172.7)
CXCL-2 pg·mL−125.8 (11.0–36.1)19.2 (10.7–47.3)13.9 (10.1–30.3)12.7 (10.5–28.6)
HMGB-1 ng·mL−110.1 (7.3–11.5)7.1 (4.6–8.5)7.1 (6.0–8.7)7.7 (5.7–10.5)
E-selectin ng·mL−1105 (57–286)148 (88.6–267.8)124 (80.4–217.3)96.9 (86.3–106.5)
NETs mean length μm76.5 (70.9–78.1)119.3 (113.8–122.6)111.2 (98.5–119.3)97.8 (86.3–106.5)
  • Data are presented as median (interquartile range). WBC: white blood cells; PLT: platelet; CRP: C-reactive protein; PCT: procalcitonin; TNF: tumour necrosis factor; IL; interleukin; CXCL: CXC ligand; HMBG-1: high-mobility group box-1.