GOLD category | |||||||||||
Total# | A¶ | B+ | C§ | Dƒ | |||||||
Total | C1## | C2¶¶ | C3++ | Total | D1§§ | D2ƒƒ | D3### | ||||
Any ICS | 253 (60) | 44 (42)¶¶¶,+++ | 28 (50)¶¶¶,+++ | 69 (59) | 26 (54)¶¶¶ | 25 (61)¶¶¶,+++ | 18 (67) | 112 (78) | 36 (68)¶¶¶ | 19 (68)¶¶¶ | 57 (90) |
Any LABA | 283 (67) | 47 (45) | 37 (66) | 80 (69) | 27 (56) | 31 (76) | 22 (81) | 119 (83) | 39 (74) | 21 (75) | 59 (94) |
Any LAMA | 223 (53) | 50 (48) | 34 (61) | 50 (43) | 27 (56) | 10 (24) | 13 (48) | 89 (62) | 28 (53) | 17 (61) | 44 (70) |
ICS alone | 9 (2)¶¶¶,+++ | 2 (2)¶¶¶,+++ | 2 (4)¶¶¶,+++ | 0 | 0 | 0 | 0 | 5 (3)¶¶¶,+++ | 1 (2)¶¶¶,+++ | 1 (4)¶¶¶,+++ | 3 (4)¶¶¶,+++ |
ICS/LABA | 99 (24) | 17 (16)¶¶¶,+++ | 8 (14)¶¶¶,+++ | 39 (34) | 9 (19) | 22 (54)¶¶¶ | 8 (30) | 35 (24) | 14 (26)¶¶¶ | 5 (18)¶¶¶ | 16 (25) |
ICS/LAMA | 8 (2) ¶¶¶,+++ | 4 (4)¶¶¶,+++ | 0 | 1 (1)¶¶¶,+++ | 1 (2)¶¶¶,+++ | 0 | 0 | 3 (3)¶¶¶,+++ | 2 (4)¶¶¶,+++ | 1 (4)¶¶¶,+++ | 0 |
ICS/LABA/LAMA | 137 (33) | 21 (20) | 18 (32)¶¶¶,+++ | 29 (25) | 16 (33)¶¶¶ | 3 (7)¶¶¶ | 10 (37) | 69 (48) | 19 (36) | 12 (43) | 38 (60) |
LABA/LAMA | 28 (7) | 4 (4) | 8 (14) | 6 (5) | 1 (2) | 3 (7) | 2 (7) | 10 (7) | 3 (6) | 2 (7) | 5 (8) |
Data are presented as n (%). ICS: inhaled corticosteroid; LABA: long-acting β2-agonist; LAMA: long-acting muscarinic antagonist. #: n=421; ¶: modified Medical Research Council (mMRC) dyspnoea score <2, forced expiratory volume in 1 s (FEV1) ≥50% predicted and fewer than two exacerbations per year, n=105 (25%); +: mMRC dyspnoea score ≥2, FEV1 ≥50% pred and fewer than two exacerbations per year, n=56 (13%); §: mMRC dyspnoea score <2, FEV1 <50% pred or two or more exacerbations per year, n=116 (28%); ƒ: mMRC dyspnoea score ≥2, FEV1 <50% pred or two or more exacerbations per year, n=144 (43%); ##: FEV1 <50% pred, n=48; ¶¶: two or more exacerbations per year, n=41; ++: both FEV1 <50% pred and two or more exacerbations per year, n=27; §§: FEV1 <50% pred, n=53; ƒƒ: more than two exacerbations per year, n=28; ###: both FEV1 <50% pred and two or more exacerbations per year, n=63; ¶¶¶: inappropriate prescription according to GOLD 2007; +++: inappropriate prescription according to GOLD 2011.