Table 3– Pulmonary function of study patients before and 6 months after weight reduction: per protocol analysis
Control group#Treatment group
Visit 0Visit 6p-valueVisit 0Visit 6p-value
FEV1 L1.64±0.131.67±0.12ns1.85±0.152.01±0.15ns
FEV1 % pred59.2±4.261.5±3.2ns64.08±3.3570.00±4.89ns
FVC L2.55±0.112.48±0.12ns2.92±0.173.16±0.160.002+
FVC % pred74.5±1.574.4±2.0ns82.42±3.1687.75±2.99ns
FEV1/FVC0.64±0.040.67±0.03ns0.64±0.030.64±0.04ns
FEF25–75% L1.08±0.181.09±0.15ns1.13±0.211.32±0.23ns
FEF25–75% % pred37.6±6.339.18±5.39ns36.75±5.7044.92±6.78ns
IC L2.16±0.112.03±0.17ns2.49±0.172.45±0.19ns
IC % pred96.7±5.693.5±7. 5ns109.00±6.08103.42±7.25ns
TLC L5.54±0.295.22±0.19ns5.70±0.265.80±0.36ns
TLC % pred111.2±3.3107.2±4.5ns113.50±4.71111.92±4.76ns
ERV L0.44±0.070.38±0.07ns0.40±0.090.73±0.17ns
ERV %41.1±6.633.9±6.1ns35.75±11.6063.67±19.45ns
RV L2.96±0.282.69±0.19ns2.80±0.262.62±0.32ns
RV % pred186.4±13.7171.0±14.0ns168.33±10.60158.75±17.54ns
RV/TLC0.53±0.030.51±0.03ns0.49±0.030.44±0.03ns
Raw cmH2O·L−1·s−14.69±0.584.10±0.54ns3.44±0.403.63±0.39ns
Raw % pred257.5±31.0220.4±29.0ns188.00±21.17202.75±20.57ns
Gaw L·s−1·cmH2O−10.16±0.030.09±0.02ns0.16±0.030.09±0.01ns
Gaw % pred31.8±6.643.2±8.1ns42.33±6.8043.08±6.79ns
  • Data are presented as mean±se unless otherwise stated. p-values were calculated by ANOVA. FEV1: forced expiratory volume in the 1 s; FVC: forced vital capacity; FEF25–75%: forced expiratory flow at 25–75% of FVC; IC: inspiratory capacity; TLC: total lung capacity; ERV: expiratory reserve volume; RV: residual volume; Raw: airway resistance; Gaw: airway conductance; ns: nonsignificant. #: n=11; : n=12; +: p=0.006 between groups.