Control group# | Treatment group¶ | |||||
Visit 0 | Visit 6 | p-value | Visit 0 | Visit 6 | p-value | |
FEV1 L | 1.64±0.13 | 1.67±0.12 | ns | 1.85±0.15 | 2.01±0.15 | ns |
FEV1 % pred | 59.2±4.2 | 61.5±3.2 | ns | 64.08±3.35 | 70.00±4.89 | ns |
FVC L | 2.55±0.11 | 2.48±0.12 | ns | 2.92±0.17 | 3.16±0.16 | 0.002+ |
FVC % pred | 74.5±1.5 | 74.4±2.0 | ns | 82.42±3.16 | 87.75±2.99 | ns |
FEV1/FVC | 0.64±0.04 | 0.67±0.03 | ns | 0.64±0.03 | 0.64±0.04 | ns |
FEF25–75% L | 1.08±0.18 | 1.09±0.15 | ns | 1.13±0.21 | 1.32±0.23 | ns |
FEF25–75% % pred | 37.6±6.3 | 39.18±5.39 | ns | 36.75±5.70 | 44.92±6.78 | ns |
IC L | 2.16±0.11 | 2.03±0.17 | ns | 2.49±0.17 | 2.45±0.19 | ns |
IC % pred | 96.7±5.6 | 93.5±7. 5 | ns | 109.00±6.08 | 103.42±7.25 | ns |
TLC L | 5.54±0.29 | 5.22±0.19 | ns | 5.70±0.26 | 5.80±0.36 | ns |
TLC % pred | 111.2±3.3 | 107.2±4.5 | ns | 113.50±4.71 | 111.92±4.76 | ns |
ERV L | 0.44±0.07 | 0.38±0.07 | ns | 0.40±0.09 | 0.73±0.17 | ns |
ERV % | 41.1±6.6 | 33.9±6.1 | ns | 35.75±11.60 | 63.67±19.45 | ns |
RV L | 2.96±0.28 | 2.69±0.19 | ns | 2.80±0.26 | 2.62±0.32 | ns |
RV % pred | 186.4±13.7 | 171.0±14.0 | ns | 168.33±10.60 | 158.75±17.54 | ns |
RV/TLC | 0.53±0.03 | 0.51±0.03 | ns | 0.49±0.03 | 0.44±0.03 | ns |
Raw cmH2O·L−1·s−1 | 4.69±0.58 | 4.10±0.54 | ns | 3.44±0.40 | 3.63±0.39 | ns |
Raw % pred | 257.5±31.0 | 220.4±29.0 | ns | 188.00±21.17 | 202.75±20.57 | ns |
Gaw L·s−1·cmH2O−1 | 0.16±0.03 | 0.09±0.02 | ns | 0.16±0.03 | 0.09±0.01 | ns |
Gaw % pred | 31.8±6.6 | 43.2±8.1 | ns | 42.33±6.80 | 43.08±6.79 | ns |
Data are presented as mean±se unless otherwise stated. p-values were calculated by ANOVA. FEV1: forced expiratory volume in the 1 s; FVC: forced vital capacity; FEF25–75%: forced expiratory flow at 25–75% of FVC; IC: inspiratory capacity; TLC: total lung capacity; ERV: expiratory reserve volume; RV: residual volume; Raw: airway resistance; Gaw: airway conductance; ns: nonsignificant. #: n=11; ¶: n=12; +: p=0.006 between groups.