| Better genetic and biomarkers of response to (controller and symptomatic) treatment |
| More RCTs of (controller) treatment using clearly characterised groups of patients, including but not limited to: |
| Symptom pattern and severity |
| Atopic sensitisation and presence of allergic disease |
| Family history of atopy, asthma and wheezing |
| Environmental exposures such as indoor allergens, tobacco smoke exposure and traffic air pollution; planned subgroup analyses of treatment response in RCTs based on the same variables or on prediction indices |
| Development and validation of better ways to assess symptoms, impact on the child’s daily activities and the parental perception of these symptoms |
RCT: randomised controlled trial.