Table 2– Clinical outcomes of study patients before and 6 months after weight reduction: per protocol analysis
Control group#Treatment group
Visit 0Visit 6p-valueVisit 0Visit 6p-value
BMI kg·m−237.29±1.0736.85±1.06ns39.88±1.8534.58±1.74<0.001***
ACQ score2.91±0.252.90±0.16ns3.04±0.251.64±0.19<0.001***
ACT score11.18±1.1512.09±0.65ns12.25±1.0817.42±1.11<0.001+
SGRQ score
 Symptoms57.41±5.9753.85±6.74ns62.41±5.1955.12±7.54ns
 Activity82.43±2.8681.17±2.95ns79.63±4.5859.97±5.14<0.001§
 Impact61.65±4.8854.40±4.28ns57.69±2.8934.18±4.71<0.001ƒ
 Total67.29±3.3762.42±3.27ns65.12±3.0245.47±4.42<0.001##
GERD-HRQL score8.00±2.9310.38±2.12ns8.20±2.268.50±1.55ns
  • Data are presented as mean±se unless otherwise stated. p-values were calculated by ANOVA. BMI: body mass index; ACQ: Asthma Control Questionnaire; ACT: Asthma Control Test; SGRQ: St George’s Respiratory Questionnaire; GERD-HRQL: Gastroesophageal Reflux Disease-Health-Related Quality-of-Life Scale; ns: nonsignificant. #: n=11; : n=12. ***: p<0.001 between groups; +: p=0.024 between groups; §: p=0.005 between groups; ƒ: p=0.028 between groups; ##: p=0.011 between groups.