Rhinovirus-positive samples | Rhinovirus infection | p-value | ||||||
Visit 1 only | Visit 1 and visit 2 | p-value | Prolonged | Re-infection | p-value | Visit 1 only versus prolonged | Visit 1 only versus re-infection | |
Patients n | 422 | 21 | 6 | 11 | ||||
Age years | 49 (35–61) | 54 (34–71) | 0.32 | 72 (44–78) | 48 (30–61) | 0.12 | 0.07 | 0.62 |
Comorbidity# | 421 | |||||||
COPD | 30 (7.1) | 6 (28.6) | 0.004 | 1 (16.7) | 3 (27.3) | 1.00 | 0.37 | 0.04 |
Asthma | 42 (10) | 5 (23.8) | 0.06 | 0 | 4 (36.4) | 0.24 | 1.00 | 0.02 |
Other lung disease | 6 (1.4) | 1 (4.8) | 0.29 | 0 | 1 (9.1) | 1.00 | 1.00 | 0.17 |
Cardiovascular | 34 (8.1) | 3 (14.3) | 0.41 | 2 (33.3) | 0 | 0.11 | 0.08 | 1.00 |
Diabetes | 26 (6.2) | 1 (4.8) | 1.00 | 0 | 1 (9.1) | 1.00 | 1.00 | 0.51 |
Previous hospitalisation for RI | 16 (3.8) | 2 (9.5) | 0.21 | 0 | 2 (18.2) | 0.52 | 1.00 | 0.07 |
Allergic disease | 73 (17.4) | 6 (28.6) | 0.24 | 1 (16.7) | 4 (36.4) | 0.60 | 1.00 | 0.11 |
Data are presented as median (interquartile range) or n (%), unless otherwise stated. COPD: chronic obstructive pulmonary disease; RI: respiratory infection. p-values were calculated using the Pearson Chi-squared or Fisher's Exact test, except for the median age, which was calculated using the Mann-Whitney U –test; #: some patients had more than one comorbidity and data on comorbidities were lacking for one patient. Bold signifies statistical significance.