COPD | Healthy | 95% CI | p-value | |
Subjects n | 21 | 24 | ||
Males % | 76.2 | 70.8 | -0.3–0.2 | 0.746 |
Age years | 64.1±7.7 | 62.4±6.2 | -2.5–5.9 | 0.410 |
Weight kg | 79.2±14.5 | 77.3±12.8 | -6.2–10.2 | 0.631 |
Height m | 1.73±0.08 | 1.74±0.09 | -0.06–0.04 | 0.682 |
BMI kg·m−2 | 26.5±4.9 | 25.4±3.3 | -1.4–3.6 | 0.379 |
GOLD stage 1/2/3/4 n | 4/10/5/2 | |||
FEV1 L | 1.73±0.66 | 3.53±0.54 | -2.2– -1.4 | <0.001 |
FEV1 % predicted | 57.8±18.9 | 117.6±19.2 | -71.3– -48.4 | <0.001 |
FVC L | 3.76±0.92 | 4.42±0.50 | -1.11– -0.19 | 0.007 |
FVC % predicted | 99.6±17.3 | 118.6±23.4 | -31.6– -6.6 | 0.004 |
Tiffeneau index % | 0.46±0.14 | 0.80±0.06 | -0.41– -0.28 | <0.001 |
Quadriceps femoris muscle | ||||
Strength Nm | 104±37 | 134±39 | -52– -7 | 0.012 |
Endurance s | 38±14 | 49±12 | -19– -4 | 0.005 |
Biceps brachii muscle | ||||
Strength Nm | 49±15 | 57±15 | -18–0 | 0.056 |
Endurance s | 60±46 | 76±28 | -38–7 | 0.170 |
Data are presented as mean±sd, unless otherwise stated. COPD: chronic obstructive pulmonary disease; BMI: body mass index; GOLD: Global Initiative for Chronic Obstructive Lung Disease; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity.