Total population | AHI events per h | p-value | ||||
0.0–6.1 | 6.2–16.0 | 16.1–34.6 | 34.7–147.3 | |||
Subjects n | 5294 | 1329 | 1329 | 1314 | 1322 | |
Males % | 70.3 | 56.4 | 66.8 | 76.0 | 82.3 | <0.001 |
Age years | 50.9±12.4 | 46.3±12.7 | 51.6±12.2 | 52.8±11.8 | 52.9±11.6 | <0.001 |
Caucasians % | 92.5 | 94.7 | 92.6 | 93.5 | 89.1 | 0.591 |
BMI kg·m−2 | 30.0±6.0 | 28.0±5.3 | 29.1±5.4 | 30.1±5.5 | 32.9±6.5 | <0.001 |
Waist circumference cm | 104.1±14.5 | 97.8±13.4 | 101.8±12.3 | 105.0±13.3 | 112.3±14.9 | <0.001 |
Neck circumference cm | 40.6±4.2 | 38.8±4.1 | 39.9±3.7 | 41.0±3.8 | 42.9±4.0 | <0.001 |
SBP mmHg | 132.1±17.4 | 128.3±16.9 | 131.0±17.3 | 133.0±16.9 | 136.2±17.4 | <0.001 |
DBP mmHg | 82.2±11.4 | 80.3±11.3 | 81.4±11.2 | 82.5±11.2 | 84.7±11.5 | <0.001 |
ESS score | 9.9±5.1 | 9.5±5.0 | 9.4±5.0 | 9.8±4.9 | 10.7±5.4 | <0.001 |
Alcohol units per week | 4.4±7.8 | 3.4±6.1 | 3.8±6.6 | 4.8±8.6 | 5.7±9.1 | <0.001 |
Smokers % | 24.2 | 25.5 | 23.3 | 23.3 | 25.1 | 0.226 |
HTN % | 35.0 | 20.9 | 32.9 | 39.1 | 47.0 | <0.001 |
IHD % | 6.1 | 3.6 | 7.4 | 6.6 | 6.8 | <0.001 |
CHF % | 1.7 | 0.9 | 1.9 | 1.6 | 2.4 | 0.03 |
Hyperlipidaemia % | 20.1 | 14.1 | 19.2 | 22.8 | 24.2 | <0.001 |
Gout % | 1.8 | 0.5 | 1.4 | 1.4 | 4.1 | <0.001 |
COPD % | 3.9 | 4.1 | 3.8 | 3.9 | 3.8 | 0.955 |
β-blockers % | 16.4 | 9.7 | 17.5 | 19.1 | 19.2 | <0.001 |
RAS drug % | 21.3 | 13.0 | 22.2 | 22.4 | 27.8 | <0.001 |
Statins % | 17.2 | 12.0 | 18.2 | 18.9 | 19.5 | <0.001 |
OCS % | 1.2 | 1.4 | 0.8 | 1.2 | 1.4 | 0.686 |
AHI events per h | 23.8±23.3 | 2.7±1.8 | 10.7±2.8 | 24.1±5.2 | 57.7±19.1 | <0.001 |
Mean SpO2 % | 93.8±3.5 | 94.9±3.0 | 94.3±2.6 | 93.9±3.2 | 92.0±4.2 | <0.001 |
ODI≥4% events per h | 18.4±22.1 | 3.1±5.0 | 8.2±7.7 | 16.7±10.3 | 46.6±25.1 | <0.001 |
Cholesterol mmol·L−1 | 5.26±1.07 | 5.26±1.02 | 5.27±1.1 | 5.28±1.1 | 5.24±1.07 | 0.348 |
Triglycerides mmol·L−1 | 1.81±1.11 | 1.59±0.90 | 1.77±1.03 | 1.89±1.20 | 2.00±1.23 | <0.001 |
Creatinine mmol·L−1 | 81.9±31.4 | 77.8±23.5 | 80.7±27.3 | 82.3±16.6 | 87.0±48.3 | <0.001 |
HbA1c % | 5.39±0.56 | 5.19±0.59 | 5.37±0.55 | 5.45±0.52 | 5.57±0.52 | <0.001 |
Data are presented as mean±sd unless otherwise stated. AHI: apnoea–hypopnoea index; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; ESS: Epworth Sleepiness Scale; HTN: hypertension; IHD: ischaemic heart disease; CHF: congestive heart failure; COPD: chronic obstructive lung disease; RAS: renin–angiotensin system; OCS: oral corticosteroids; SpO2: arterial oxygen saturation measured by pulse oximetry; ODI: oxyhaemoglobin desaturation index; HbA1c: glycosylated haemoglobin.